Substrate: Pyruvate dehydrogenase kinase isoform 1 (Enzyme: Phosphotransferase)
Seq-ID: Q15118 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-2881402   SGK3_HUMAN
MINT-3390512   KS6B1_HUMAN
MINT-3390627   PKN2_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
ATP binding,
pyruvate dehydrogenase (acetyl-transferring) kinase activity,
two-component sensor activity		 mitochondrial matrix peptidyl-histidine phosphorylation,
regulation of acetyl-CoA biosynthetic process from pyruvate,
small GTPase mediated signal transduction,
glucose metabolic process
Conservation:
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Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 25 PGPGLRAAGFSRSFSSDSGSS - 12177059
LTP
0.33
 - -
0.43
 --
S 393 TDAVIYIKALSTDSIERLPVY - 12177059
LTP
0.95
 - HATPase_c
0.13
 2Q8F 19.67%
S 396 VIYIKALSTDSIERLPVYNKA - 12177059
LTP
0.95
 - -
0.12
 2Q8F 0.82%

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